Difference Between PRP PRF Bio Filler

What are PRP and I-PRF treatments, and how do they differ?

Platelets are the cells that promote blood clotting, playing a vital role in tissue repair and regeneration. Platelets are the cells that promote blood clotting, playing a vital role in tissue repair and regeneration. Also known as thrombocytes, platelets are small, colourless cell fragments in our blood that form clots and stop or prevent bleeding. Platelets also release a variety of mediators including different growth factors that can trigger cell reproduction and stimulate healing in the area they are in the different treatments we offer.

PRP (Platelet-Rich Plasma) we generally microneedle and I-PRF (Injectable Platelet Rich Fibrin) are both advanced regenerative therapies using components of your blood. PRP focuses on platelet-rich plasma, while I-PRF includes fibrin, a protein that aids in healing. Both treatments stimulate skin rejuvenation but have subtle differences in their composition and application.

These treatments are ideal for individuals seeking to improve skin texture, reduce signs of aging, and promote natural healing. They are particularly effective for those looking to enhance their skin’s appearance using a natural approach. If your client does not like injections and needles, then the PRP microneedling would be better.

PRP and PRF are natural growth factors found in your own blood. Rich in platelets, white blood cells, and fibrin (in the case of PRF), these substances stimulate the production of collagen, elastin, and new skin cells. Both treatments are effective in treating fine lines and wrinkles, and improving tone and texture, and fading dark spots and other signs of aging.

PRP is a full-face skin rejuvenation with a microneedling pen and iPRF are injections and are typically used to treat under eye dark circles, nasolabial folds, cheeks, smile lines, lips, and loss of volume on targetted areas of the face, neck and body. Both can used on the scalp to stimulate hair growth and can be used to firm the hands, décolleté, and for neck rejuvenation.

Whilst PRP is the most well-known treatments of this kind, Platelet Rich Fibrin (or PRF) is growing in popularity which we have taught this course for over 8 years now. PRF can be used in several versatile ways – so, what is PRF and why is it different to PRP?

PRP tubes will contain a chemical compound which stops the blood sample from coagulating and forming a hard clot. There are different options available for anti-coagulation, but Sodium Citrate (which hospitals use to store blood for blood-transfusions) is the most common and very safe.

On the other hand, PRF tubes contain no anticoagulant. This means that left to its own devices and when exposed to oxygen, the blood sample taken from a patient will form a solid clot.

So, most practitioners use injections for the PRF platelet rich plasma for targeting areas of concerns on the face

The clot of the PRF tube can be used in dentistry during implant preparation, in sports therapy to speed-up the healing of joints, or in cosmetics. Alternatively, as coagulation takes time.

As skin experts in Aesthetic practice, we use PRF an injectable liquid for (depending on the brand of supplier) for up to 16 minutes. This is an option for practitioners trying to provide the most autologous procedure, without the introduction of any foreign substances (like anti-coagulants). With a PRF treatment, a fibrin matrix is created, which releases growth factors and other elements more slowly over time. This means that while PRP releases these healing factors for 2-3 days, PRF releases them over 2-3 weeks.

What is Platelet-Rich Fibrin (PRF)?

Platelet-rich fibrin (PRF) is made by mixing blood from a patient with a calcium chloride solution. This technique creates a fibrin matrix. As a recent development in the realm of medical aesthetics, PRF uses fibrin to make a structure that holds platelets in place.

What is Platelet Rich Plasma (PRP)?

Platelet-rich-plasma (PRP) is just a way of isolating these platelets and reinjecting them into a localised area to stimulate a natural healing process. The practitioner first takes a sample of blood from the patient, usually in a 10ml vial. This is then placed into a centrifuge, which separates the different components in the blood due to the gravitational force it is exposed to during centrifugation. The red blood cells and buffy coat are pushed to the bottom, whereas the Platelet-rich-plasma – a gold-coloured liquid – will settle at the top. This is then harvested and administered as a treatment in several therapeutic applications, including aesthetics, hair regrowth, dermatology, orthopaedics, veterinary treatments and more. Depending on the treatment, a practitioner may centrifuge the blood at a different speed, to create a concentrated PRP layer.

What are Bio Fillers?

Whereas PRP therapy can benefit a wide range of people and requirements, PRP Fillers are most suitable for those who have loss of facial volume resulting in lines, creases, lack of definition and general sagginess. These patients might otherwise have considered an injectable filler, but PRP Fillers offer a more natural solution by using the powerful healing factors held within the patient’s own blood and avoiding any use of artificial substances. They are used for contouring and a filling effect; they do not have a skin rejuvenation ability or PRF & PRP but can be used in conjunction of them.

Plasma Filler is rich in albumin and fibrinogen, a precursor to fibrin which binds to platelets and hyaluronic acid. Hyaluronic acid stimulates fibroblasts. The three-dimensional matrix serves as a template or scaffold and massively traps the platelets, growth factors, leukocytes, cytokines, and mesenchymal stem cells during the remodelling of tissue.

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Contact us on 0117 287 2377 or email klaire@bristolbeautyaestheticstraining.co.uk.